关键词: 猫, 实验动物, 血细胞计数, 血生化, 范围

Abstract: Objective The purpose of this investigation is to explore the range of blood physiological and biochemical indicators of healthy cats ( in good condition without reported disease history) , and the influence of factors including gender and age on these indicators, further to promote the standardization of cats as experimental animals. Method Domestic cats were recruited from Wuhan city as the research subjects, and 75 healthy cats were screened by completely random method . Blood was collected to detect blood cell count and blood biochemical indicators. Then statistical analysis was performed. Result The range of blood cell count indexes and blood biochemical indexes of healthy cats were preliminarily clarified. It was found that the blood cell count and most physiological and biochemical indexes excluding AST ( P< 0. 05) were not significantly influenced by age but not gender of cats. The white blood cell, monocyte, and neutrophil counts had a decrease tendacy with age. Contrarily, hematocrit and average hemoglobin concentration in red blood cells were all increased with age. As the age increasing, the concentration of phosphorus and calcium ions in blood showed a downward trend, while the indicators such as creatinine, cholesterol, globulin and random blood sugar showed an upward trend. Conclusion This study preliminarily explored the normal range of cat’ s blood physiological and biochemical indicators, and found that theses indicators were significantly affected by aging. The result provided a basis for promoting cats as standard experimental animals. Meanwhile, this study suggests that cats of different ages have different nutritional needs, providing theoretical guidance for precision feeding and health care for cats.

Key words: cat, experimental animal, blood cell count, blood biochemistry, range